Gene information
Official symbol SHC2
Official full name SHC adaptor protein 2
Gene type protein-coding gene
Chromosome19p13.3
Alias symbolSLI; SCK; SHCB
Gene familySH2 domain containing
Resources
Entrez Gene 25759
HGNC HGNC:29869
Ensembl ENSG00000129946
Vega OTTHUMG00000180545
UCSC uc002loq.4
GO terms: 8 records
GO Description Category LogP Number of genes Detail
GO:0007167 enzyme-linked receptor protein signaling pathway GO Biological Processes -26.8285253 93 More
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway GO Biological Processes -16.7048742 60 More
GO:0019900 kinase binding GO Molecular Functions -6.03057706 62 More
GO:0019901 protein kinase binding GO Molecular Functions -6.66055444 59 More
GO:0030971 receptor tyrosine kinase binding GO Molecular Functions -4.12949610 12 More
GO:0043408 regulation of MAPK cascade GO Biological Processes -57.2547066 142 More
GO:0043410 positive regulation of MAPK cascade GO Biological Processes -49.4744054 112 More
GO:1990782 protein tyrosine kinase binding GO Molecular Functions -4.10270724 15 More
KEGG pathways: 6 records
KEGG Description Category LogP Number of genes Detail
hsa04014 Ras signaling pathway KEGG Pathway -9.01898803 33 More
hsa04072 Phospholipase D signaling pathway KEGG Pathway -3.77257282 17 More
hsa04510 Focal adhesion KEGG Pathway -16.5268196 41 More
hsa04935 Growth hormone synthesis, secretion and action KEGG Pathway -2.82078524 13 More
hsa05224 Breast cancer KEGG Pathway -6.01672252 21 More
hsa05226 Gastric cancer KEGG Pathway -5.33653529 20 More
Related study: 1 record
Molecular factor Omics type Application Objective MI type Reference
cg05537380 hypermethylation epigenomics myocardial infarction[diagnosis] myocardial infarction Rask-Andersen M et al. Hum Mol Genet. 2016
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